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Polyclonal Rabbit Anti-Human
Kappa Light Chains
These reagents have been produced in a manner that ensures a particularly wide specificity for kappa-chains. Most B cells, with the exception of pre-B progenitors, pre-B cells and mature plasma cells, express immunoglobulin on their surface. Each cell expresses only one light chain type. In normal peripheral blood and lymph nodes there is a mixture of kappa+ and lambda+ cells with two-thirds of the cells expressing kappa and one-third expressing lambda (1).
The reagents are of value for the demonstration of the monoclonal nature (light chain restriction) of lymphoid neoplasms.
References
- Johnson A, Olofsson T. Flow cytometric clonal excess analysis of peripheral blood, routine handling, and pitfalls in interpretation. Cytometry 1993;14:188-95.
| Product | Size |  | C0222 APC. Affinity-isolated F(ab')2
| 100 tests, 1 mL Product No. C022201 | | F0434 FITC. Affinity-isolated F(ab')2
| 100 tests, 1 mL Product No. F043401 | | R0436 RPE. Affinity-isolated F(ab')2
| 100 tests, 1 mL Product No. R043601 |
|---|