c-Kit pharmDx™ is a qualitative immunohistochemical kit system for the identification of c-kit (CD117) protein expression in normal and neoplastic tissues. c-Kit pharmDx™ is indicated as an aid in the differential diagnosis of gastrointestinal stromal tumors (GIST). Accurate assessment of c-kit protein expression is now a critical factor in the diagnosis of GIST and is becoming increasingly important in influencing decisions regarding clinical management, including the use of Gleevec®/Glivec® (imatinib mesylate) for the treatment of patients with confirmed GIST.

c-Kit pharmDx™ utilizes a simple two-step staining procedure and is suitable for formalin-fixed, paraffin-embedded specimens. The kit includes ready-to-use primary antibody, negative control reagent, cell line control slides and detailed instructions. The kit has been tailored especially for use on the Dako Autostainer.