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Monoclonal Rabbit Anti-Human
Estrogen Receptor α
This monoclonal rabbit antibody reacts with human estrogen receptor α (ER α).
Estrogens have been found to be preferentially concentrated in the estrogen target organs of animals and in human breast cancers, and it is well documented that the mitogenic effects of estrogen are mediated by ER. Historical studies have shown that ER status is correlated with untreated outcome (i.e. prognostic for well-differentiated invasive breast cancer) and with response to anti-hormonal therapy, e.g. tamoxifen (1). The antibody may be used in the semi-quantitative detection of human estrogen receptor in tissue sections of human breast cancer by immunohistochemistry.
Breast carcinoma with positive estrogen receptor expression. The neoplastic cells show a moderate to strong staining reaction.
Clinical application for IR084/IS084. For assessment of estrogen receptor status in breast carcinomas.
Disclaimer: Due to variances among color computer monitors, the colors you see on your screen may not be the exact colors of the stain. The image you see should be considered close renditions to the actual stain.
- Optimized staining performance of both high- and low-expression structures
- Crisp and clear staining with no background
- Optimal laboratory efficiency with ready-to-use antibodies on Dako Autostainer Plus
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|Product||Size||IS084 Clone EP1||30 tests, 6 mL |
Packaged in vials for use with Dako Autostainer instruments
Product No. IS08430-2
Synonym(s) for Antigen
ERα, ER alpha, ER