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BCL2 DNA Probe, Fluorochrome-Conjugated
The human BCL2 gene consists of 3 exons spanning a region of ~195 kb on chromosome 18 band q21. Y5407 is a probe based on a combination of DNA and PNA technology, and contains a two-part fluorochrome-conjugated DNA probe and unlabeled PNA blocking probes. The fluorochrome-conjugated DNA probe is a Texas Red-labeled DNA probe (BCL2-Upstream) covering 375 kb telomeric to the BCL2 major/minor breakpoint cluster regions and a fluorescein-labeled DNA probe (BCL2-Downstream) covering 641 kb centromeric to the BCL2 major/minor breakpoint cluster regions.