TCRG DNA Probe, Fluorochrome-Conjugated

The human T-cell receptor gamma (TCRG) locus at chromosome 7 consists of 21 genes. These genes are devided into 11 variable (TCRGV) genes, 3 diversity (TCRGD) gene segments, 5 joining (TCRGJ) gene segments, and 2 constant (TCRGC) genes. The TCR locus spans a region of ~156 kb on chromosome 7 band p14. Y5420 is a probe based on a combination of DNA and PNA technology, and contains a two-part fluorochrome-conjugated DNA probe and unlabeled PNA blocking probes. The fluorochrome-conjugated DNA probe is a Texas Red-labeled DNA probe (TCRG-Downstream) covering 290 kb centromeric to the TCRG breakpoint cluster region and a fluorescein-labeled DNA probe (TCRG-Upstream) covering 590 kb telomeric to the TCRG breakpoint cluster region.

ProductSDS (Safety Data Sheet)Size
Analyte Specific Reagent. Analytical and performance characteristics are not establishedY5420 Probe (containing Formamide)
0.2 mL
Product No. Y542029

Schematic illustration of TCRG FISH DNA Probe hybridization regions.

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