Monoclonal Mouse Anti-Human


Clone L26

CD20 is a transmembrane, non-glycosylated protein expressed on B-cell precursors and mature B cells, but is lost following differentiation into plasma cells. In resting B cells, CD20 appears in a 33 kDa non-phosphorylated form. After mitogen stimulation, CD20 becomes heavily phosphorylated (35-37 kDa isoforms), and it is a dominant phosphoprotein in activated B cells. The antibody reacts with an intracytoplasmic epitope localized on the CD20 antigen and labels cells of the B-cell lineage. It is a useful tool for the classification of neoplasms of B-cell derivation.

B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma (FFPE) stained with FLEX Anti-CD20cy, Code IR604/IS604.

B-cell chronic lymphocytic leukemia/small lymphocyticlymphoma. The majority of the neoplastic cells show a distinct membranous staining reaction.

Clinical application for IR604/IS604. For identification of the B-cell lineage and different types of B-cell lymphoma like mantle cell lymphoma

Disclaimer: Due to variances among color computer monitors, the colors you see on your screen may not be the exact colors of the stain. The image you see should be considered close renditions to the actual stain.

  • Optimized staining performance of both high and low-expression structures
  • Crisp and clear staining with no background
  • Optimal laboratory efficiency with ready-to-use antibodies on Dako Autostainer Plus
The staining performance of all antibodies has been defined, tested and approved through collaboration with leading international pathologists. Check the Atlas of Stains - a guide to diagnostic accuracy.

This product is CE-marked according to the EU IVD Directive 98/79/ECIS604 Clone L26
Safety Data Sheet:
Non-hazard classification statement
30 tests, 6 mL
Product No. IS60430



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