MLL FISH DNA Probe, Split Signal

The human MLL (ALL-1, HTRX1, HRX) gene consists of 37 exons spanning a region of 86 kb on chromosome 11 band q23. Y5401 is a probe mix based on a combination of DNA and PNA technology, and contains two ready-to-use FISH DNA probes and unlabeled PNA blocking probes. The FISH DNA probes are a mixture of a Texas Red-labeled DNA probe (MLL-Upstream) covering 239 kb centromeric to the MLL breakpoint cluster region and a fluorescein-labeled DNA probe (MLL-Downstream) covering 513 kb telomeric to the MLL breakpoint cluster region.

Precursor B-ALL with MLL gene translocation.

Disclaimer: Due to variances among color computer monitors, the colors you see on your screen may not be the exact colors of the stain. The image you see should be considered close renditions to the actual stain.

ProductSDS (Safety Data Sheet)Size
This product is CE-marked according to the EU IVD Directive 98/79/ECY5401 Probe containing Formamide
 

Schematic illustration of MLL FISH DNA Probe hybridization regions.

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Pathology Products
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Y. Huseynov 6

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