SIL-TAL1 FISH DNA Probe, Sub-Deletion Signal

The human SIL gene consists of 18 exons spanning a region of 64 kb. The human TAL1 (SCL) gene consists of 6 exons spanning a region of 16 kb. Both genes are located on chromosome 1 band p32. Y5405 is a probe mix based on a combination of DNA and PNA technology, and contains two ready-to-use FISH DNA probes and unlabeled PNA blocking probes. The FISH DNA probes are a mixture of a Texas Red-labeled DNA probe (SIL) covering 67 kb of the deletion area and a fluorescein-labeled DNA probe covering 566 kb telomeric to the deletion area.

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T-ALL with SIL-TAL1 gene fusion caused by sub-deletion.

Disclaimer: Due to variances among color computer monitors, the colors you see on your screen may not be the exact colors of the stain. The image you see should be considered close renditions to the actual stain.

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This product is CE-marked according to the EU IVD Directive 98/79/ECY5405
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Not available online, please contact Dako
20 tests, 0.2 mL
Product No. Y540529

Schematic illustration of SIL-TAL1 FISH DNA Probe hybridization regions.

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