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IGL FISH DNA Probe, Split Signal
The human IGL locus at chromosome 22 consists of at least 84 genes. These genes are devided into 70 variable (IGLV) genes, 7 joining (IGLJ) gene segments, and 7 constant (IGLC) genes. The IGL locus spans a region of ~911 kb on chromosome 22 band q11. Y5412 is a probe mix based on a combination of DNA and PNA technology, and contains two ready-to-use FISH DNA probes and unlabeled PNA blocking probes. The FISH DNA probes are a mixture of a Texas Red-labeled DNA probe (IGL-Downstream) covering 343 kb telomeric to the IGL breakpoint cluster region and a fluorescein-labeled DNA probe (IGL-Upstream) covering 829 kb centromeric to the IGL breakpoint cluster region.
IGL gene translocation, Courtesy of Euro-FISH.
Disclaimer: Due to variances among color computer monitors, the colors you see on your screen may not be the exact colors of the stain. The image you see should be considered close renditions to the actual stain.
| Product | Size |  | Y5412
| 20 tests, 0.2 mL Product No. Y541229 |
|---|
Schematic illustration of IGL FISH DNA Probe hybridization regions.