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IGK FISH DNA Probe, Split Signal
The human IGK locus at chromosome 2 consists of at least 82 genes. These genes are divided into 76 variable (IGKV) genes, 5 joining (IGKJ) gene segments, and 1 constant (IGKC) gene. The IGK locus spans a region of ~1820 kb on chromosome 2 band p11. Y5416 is a probe mix based on a combination of DNA and PNA technology, and contains two ready-to-use FISH DNA probes and unlabeled PNA blocking probes. The FISH DNA probes are a mixture of a Texas Red-labeled DNA probe (IGK-Downstream) covering 227 kb telomeric to the IGK breakpoint cluster region, and a fluorescein-labeled DNA probe (IGK-Upstream) covering ~870 kb centromeric to the IGK breakpoint cluster region.
IGK gene translocation, Courtesy of Euro-FISH.
Disclaimer: Due to variances among color computer monitors, the colors you see on your screen may not be the exact colors of the stain. The image you see should be considered close renditions to the actual stain.
| Product | Size |  | Y5416
| 20 tests, 0.2 mL Product No. Y541629 |
|---|
Schematic illustration of IGK FISH DNA Probe hybridization regions.