The MYC (c-Myc) gene located on chromosome 8q24 spans approximately 5 kb and contains 3 exons. MYC/CEN-8 FISH Probe Mix detects the copy number of the MYC gene using the chromosome 8 centromere region as a reference. Y5504 is based on a combination of PNA and DNA technology, and contains a 291 kb Texas Red-labeled DNA probe covering the full MYC region and fluorescein-labeled PNA probes targeted at the centromeric region of chromosome 8. The probe mix also contains unlabeled PNA oligos directed towards repetitive sequences in the genome to diminish unspecific staining.