Monoclonal Mouse Anti-Human

Beta-Catenin

Clone β-Catenin-1

Beta-catenin is an 88 kDa multifunctional protein playing an essential role in cell-cell adhesion by binding to the transmembrane protein, cadherin.

Beta-catenin is also involved in the regulation of gene expression as a mediator of the Wnt signaling pathway. The expression and intracellular localization of beta-catenin is altered in many types of cancers. Besides the reactivity with human beta-catenin, the M3539 antibody cross-reacts with mouse beta-catenin.

Colon adenoma (FFPE) stained with FLEX Anti-Beta-Catenin, Code IR702/IS702.

Colon adenoma. The majority of the dysplastic cells show a moderate to strong nuclear staining reaction with weaker costaining of cytoplasm.

Clinical application for IR702/IS702.For identification of desmoid tumors, colorectal cancer and colon adenoma.

Disclaimer: Due to variances among color computer monitors, the colors you see on your screen may not be the exact colors of the stain. The image you see should be considered close renditions to the actual stain.

  • Optimized staining performance of both high and low-expression structures
  • Crisp and clear staining with no background
  • Optimal laboratory efficiency with ready-to-use antibodies on Autostainer Link 48
The staining performance of all antibodies has been defined, tested and approved through collaboration with leading international pathologists. Check the Atlas of Stains - a guide to diagnostic accuracy.

ProductSize
This product is CE-marked according to the EU IVD Directive 98/79/ECIR702 Clone β-Catenin-1
Safety Data Sheet:
Non-hazard classification statement
60 tests, 12 mL
Product No. IR70261

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