Polyclonal Rabbit Anti-Human

CD3

Synthetic peptide from the intracellular part of the ε-chain of human CD3 was coupled to bovine thyroglobulin and used for immunization.

The antibody is a pan-T cell marker for detection of normal and neoplastic T cells. It is well-suited for detecting reactive T cells in tissue with lymphoid infiltrates, and for diagnosing T-cell neoplasms. The antibody cross-reacts with T cells in many animal species (1). In conjunction with Dako Monoclonal Mouse Anti-Human CD20cy (Code M0755), the antibody is well-suited for the differentiation between T and B cells in formalin-fixed tissue (2). Futhermore, antibodies against CD3 may aid in the differential diagnosis of Hodgkin's disease where CD3 is rarely expressed (3).

The antibody shows a stronger labeling intensity than corresponding monoclonal antibodies to CD3, and should, generally, be preferred on formalin-fixed, paraffin-embedded tissue sections.

Peripheral T-cell lymphoma (FFPE) stained with FLEX Anti-CD3, Code IR503/IS503.

Peripheral T-cell lymphoma. The majority of the neoplastic cells show a distinct membranous and cytoplasmic staining reaction.

Clinical application for IR503/IS503. For identification of T cells and their neoplasms such as T- and/or NK-cell lymphomas and mycosis fungoides.

Disclaimer: Due to variances among color computer monitors, the colors you see on your screen may not be the exact colors of the stain. The image you see should be considered close renditions to the actual stain.

  • Optimized staining performance of both high and low-expression structures
  • Crisp and clear staining with no background
  • Optimal laboratory efficiency with ready-to-use antibodies on Dako Autostainer Plus
The staining performance of all antibodies has been defined, tested and approved through collaboration with leading international pathologists. Check the Atlas of Stains - a guide to diagnostic accuracy.

ProductSize
This product is CE-marked according to the EU IVD Directive 98/79/ECIS503
Safety Data Sheet:
Non-hazard classification statement
30 tests, 6 mL
Product No. IS50330

Synonym(s)

CD3 complex, T3

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