TLX3 FISH DNA Probe, Split Signal

The human TLX3 (HOX11L2, RNX) gene consists of 3 exons spanning a region of 2.2 kb on chromosome 5 band q35 and is located 10.5 kb telomeric to the RANBP17 gene. Y5404 is a probe mix based on a combination of DNA and PNA technology, and contains two ready-to-use FISH DNA probes and unlabeled PNA blocking probes. The FISH DNA probes are a mixture of a Texas Red-labeled DNA probe (TLX3-Upstream) covering 192 kb centromeric to the TLX3 breakpoint cluster region and a fluorescein-labeled DNA probe (TLX3-Downstream) covering 368 kb telomeric to the TLX3 breakpoint cluster region.

Precursor B-ALL with TLX3 gene translocation.

Disclaimer: Due to variances among color computer monitors, the colors you see on your screen may not be the exact colors of the stain. The image you see should be considered close renditions to the actual stain.

ProductSDS (Safety Data Sheet)Size
This product is CE-marked according to the EU IVD Directive 98/79/ECY5404 Probe (containing Formamide)
20 tests, 0.2 mL
Product No. Y540429-2

Schematic illustration of TLX3 FISH DNA Probe hybridization regions.

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