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EGFR/CEN-7 FISH Probe Mix
The EGFR (epidermal growth factor receptor) gene located on chromosome 7p11.2 spans approximately 188 kb and contains 28 exons. EGFR/CEN-7 FISH Probe Mix detects the copy number of the EGFR gene using the chromosome 7 centromere region as a reference. Y5500 is based on a combination of PNA and DNA technology, and contains a 196 kb Texas Red-labeled DNA probe covering the full EGFR gene and fluorescein-labeled PNA probes targeted at the centromeric region of chromosome 7. The probe mix also contains unlabeled PNA oligos directed towards repetitive sequences in the genome to diminish unspecific staining.
Disclaimer: Due to variances among color computer monitors, the colors you see on your screen may not be the exact colors of the stain. The image you see should be considered close renditions to the actual stain.
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| Product | SDS (Safety Data Sheet) | Size |  | Y5500 | Probe (containing Formamide) | 20 tests, 0.2 mL Product No. Y550029-8 |
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Schematic illustration of EGFR/CEN-7 FISH DNA Probe Mix hybridization regions.