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Monoclonal Mouse Anti-Human
Progesterone Receptor
Clone PgR 636
Progesterone receptor (PR) is a steroid hormone receptor that plays an important role in breast cancer. The absence of PR and estrogen receptor (ER) predicts early recurrence and poor survival of breast cancer patients.
The antibody to PR is useful for measuring the relative level of expression of progesterone receptor in breast cancer tissue. This antibody is indicated for use as an aid in the management, prognosis and prediction of outcome of breast cancer.
Breast ductal carcinoma (FFPE) stained with FLEX Anti-Progesterone Receptor.
Breast ductal carcinoma. The neoplastic cells show a strong nuclear staining reaction
Clinical application. For measuring of the relative level of expression for progesterone receptor in breast cancer tissue. It also labels meningioma cells.
Disclaimer: Due to variances among color computer monitors, the colors you see on your screen may not be the exact colors of the stain. The image you see should be considered close renditions to the actual stain.
- Optimized staining performance of both high- and low-expression structures
- Crisp and clear staining with no background
- Optimal laboratory efficiency with ready-to-use antibodies on Dako Autostainer Plus
FLEX Monoclonal Mouse Anti-Human Progesterone Receptor, Clone PgR 636, Ready-to-Use (Dako Autostainer/Autostainer Plus), is intended for use in immunohistochemistry together with Dako Autostainer/Autostainer Plus instruments. This antibody is useful for measuring the relative level of expression for progesterone receptor in breast cancer tissue. This antibody is indicated for use as an aid in the management, prognosis and prediction of outcome of breast cancer. The clinical interpretation of any staining or its absence should be complemented by morphological studies using proper controls and should be evaluated within the context of the patient's clinical history and other diagnostic tests by a qualified pathologist.
Clone: PgR 636 (1). Isotype: IgG1, kappa.
- Press M, Spaulding B, Groshen S, Kaminsky D, Hagerty M, Sherman L, Christensen K, Edwards DP. Comparison of different antibodies for detection of progesterone receptor in breast cancer.
Steroids 2002;67:799-813.
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| Product | Size |  | IS068 Clone PgR 636
| 30 tests, 6 mL Product No. IS06830-2 |
|---|
RECOMMENDED COMPANION PRODUCTS
| Step | Product | Size |
|---|---|---|
| Pre-treatment | EnVision™ FLEX Target Retrieval Solution, High pH (Code K8004) 3-in-1 procedure using PT Link | 3 x 30 mL Product No. K800421-2 |
| Antibody Dilution | Ready-to-use / Prediluted | |
| Negative Control | FLEX Negative Control, Mouse (Code IS750) Positive tissue: Cervix and breast tissue | 60 tests, 12 mL Product No. IS75061-2 |
| Visualization System | EnVision™ FLEX+ (Code K8012) Use High pH Target Retrieval Solution | 400-600 tests Product No. K801221-2 |
| Counterstain | Hematoxylin (Dako Autostainer/Autostainer Plus) (Code K8018) Non-aqueous, permanent mounting medium is required | 10 x 13 mL, 400-600 tests Product No. K801821-2 |
| Glass Slides | Silanized Slides (Code S3003) Recommended for greater adherence Alternative is FLEX IHC Microscope Slides (Code K8020) | 100 slides Product No. S300330-2 |
Synonym(s) for Antigen
PR, PgR636