Monoclonal Mouse Anti-Human

Actin (Muscle)

Clone HHF35

Labels myocardial, skeletal and smooth muscle cells as well as myoepithelial cells.

The antibody recognizes rhabdomyosarcomas, leiomyomas and leiomyosarcomas, and also reacts with 'myofibroblasts' in the stroma of certain tumors including many carcinomas.

Isotype IgG1, kappa

  • Frozen
  • Formalin
  • HIER

Leiomyosarcoma (FFPE) stained with FLEX Anti-Actin (Muscle), Code IR700/IS700.

Leiomyosarcoma. The majority of the neoplastic cells show a moderate to strong staining reaction.

Clinical application for IR700/IS700. For identification of soft tissue tumors with muscle differentiation, i.e. leiomyoma, leiomyosarcoma and rhabdomyosarcoma.

Rhabdomyosarcoma. The majority of the neoplastic cells show a weak to moderate staining reaction.

Clinical application for IR700/IS700. For identification of soft tissue tumors with muscle differentiation, i.e. leiomyoma, leiomyosarcoma and rhabdomyosarcoma.

Colon. All the smooth muscle cells in vessel walls, lamina muscularis mucosa and myoepithelial cells around colonic crypts show a moderate to strong staining reaction. No staining reaction should be seen in the epithelial cells.

Recommended control for IR700/IS700. Appendix/Colon/Tongue.

Tongue. The myoepithelial cells of the mucous/salivary glands show a weak to moderate staining reaction.

Recommended control for IR700/IS700. Appendix/Colon/Tongue.

Leiomyosarcoma stained with Anti-Actin (Muscle).

Clinical application for IR700/IS700. For identification of soft tissue tumors with muscle differentiation, i.e. leiomyoma, leiomyosarcoma and rhabdomyosarcoma.

Disclaimer: Due to variances among color computer monitors, the colors you see on your screen may not be the exact colors of the stain. The image you see should be considered close renditions to the actual stain.

  • Excellent specificity
  • High lot to lot consistency
  • Optimized for immunohistochemistry (IHC) with validated protocols
  • Certified manufacturing facilities guarantee full quality control
Dako's products are the result of almost 50 years experience ensuring quality and innovation in antibodies and reagents: the genesis of the pathology lab of tomorrow.

ProductSize
This product is CE-marked according to the EU IVD Directive 98/79/ECM0635 Culture supernatant
Safety Data Sheet:
Non-hazard classification statement
1 mL
Product No. M063501

  • Optimized staining performance of both high and low-expression structures
  • Crisp and clear staining with no background
  • Optimal laboratory efficiency with ready-to-use antibodies on Autostainer Link 48
The staining performance of all antibodies has been defined, tested and approved through collaboration with leading international pathologists. Check the Atlas of Stains - a guide to diagnostic accuracy.

ProductSize
This product is CE-marked according to the EU IVD Directive 98/79/ECIR700 RTU, FLEX
Safety Data Sheet:
Non-hazard classification statement
60 tests, 12 mL
Product No. IR70061

RECOMMENDED COMPANION PRODUCTS

StepProductSize
Pre-treatmentEnVision™ FLEX Target Retrieval Solution, High pH (Code K8004)
3-in-1 procedure using PT Link
3 x 30 mL
Product No. K800421
Antibody Dilution
Ready-to-use / Prediluted
 
Negative ControlFLEX Negative Control, Mouse (Code IS750)
Positive tissue: Colon and tongue
60 tests, 12 mL
Product No. IS75061
Visualization SystemEnVision™ FLEX (Code K8010)
Use High pH Target Retrieval Solution
400-600 tests
Product No. K801021
CounterstainHematoxylin (Dako Autostainer/Autostainer Plus) (Code K8018)
Non-aqueous, permanent mounting medium is required
10 x 13 mL, 400-600 tests
Product No. K801821
Glass SlidesFLEX IHC Microscope Slides (Code K8020)
Recommended for greater adherence
5 x 100 slides
Product No. K802021

  • Optimized staining performance of both high and low-expression structures
  • Crisp and clear staining with no background
  • Optimal laboratory efficiency with ready-to-use antibodies on Dako Autostainer Plus
The staining performance of all antibodies has been defined, tested and approved through collaboration with leading international pathologists. Check the Atlas of Stains - a guide to diagnostic accuracy.

ProductSize
This product is CE-marked according to the EU IVD Directive 98/79/ECIS700 RTU, FLEX
Safety Data Sheet:
Non-hazard classification statement
30 tests, 6 mL
Product No. IS70030

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