Monoclonal Mouse Anti-Human

Cytokeratin 7

Clone OV-TL 12/30

Reacts with the 54 kDa protein corresponding to cytokeratin 7.

The antibody labels several types of normal and neoplastic epithelia, including many ductal and glandular epithelia. Clone OV-TL 12/30 has been found useful for the identification of adenocarcinomas of the lung, breast and endometrium, thyroid gland and ovary, as well as chromophobe renal cell carcinomas. Antibodies to cytokeratin 7 may also be useful in the differential diagnosis of prostate carcinomas where CK7 is rarely expressed.

Isotype IgG1, kappa

  • Frozen
  • Formalin
  • Enzyme/HIER

Serous ovarian carcinoma (FFPE) stained with FLEX Anti-Cytokeratin 7, Code IR619/IS619.

Serous ovarian carcinoma. A strong cytoplasmic staining reaction is seen in the neoplastic cells.

Clinical application for IR619/IS619. For identification of tumors of unknown origins and for staining of cytokeratin 7 in glandular and transitional epithelial cells appearing in various tumors.

Breast lobular carcinoma. The majority of the neoplastic cells show a distinct and predominantly cytoplasmic, but also membrane accentuated staining reaction.

Clinical application for IR619/IS619. For identification of tumors of unknown origins and for staining of cytokeratin 7 in glandular and transitional epithelial cells appearing in various tumors.

Pancreas. The epithelial cells of the large acinar ducts show a moderate to strong staining reaction, whereas the epithelial cells of the intercalating pancreatic ducts show a weak to moderate staining reaction. The pancreatic acinar cells are negative.

Recommended control for IR619/IS619. Pancreas/Breast.

Disclaimer: Due to variances among color computer monitors, the colors you see on your screen may not be the exact colors of the stain. The image you see should be considered close renditions to the actual stain.

  • Excellent specificity
  • High lot to lot consistency
  • Optimized for immunohistochemistry (IHC) with validated protocols
  • Certified manufacturing facilities guarantee full quality control
Dako's products are the result of almost 50 years experience ensuring quality and innovation in antibodies and reagents: the genesis of the pathology lab of tomorrow.

ProductSize
For In Vitro Diagnostic UseM7018 Culture supernatant
Safety Data Sheet:
Non-hazard classification statement
0.2 mL
Product No. M701829-2
1 mL
Product No. M701801-2

  • Optimized staining performance of both high and low-expression structures
  • Dako Omnis and the dynamic gap staining technology provides a consistent, uniform staining with excellent morphology
  • Crisp and clear staining with no background
  • Optimal laboratory efficiency with ready-to-use antibodies on Dako Omnis
The staining performance of all antibodies has been defined, tested and approved through collaboration with leading, international pathologists.

ProductSize
For In Vitro Diagnostic UseGA619 RTU, FLEX
Safety Data Sheet:
Non-hazard classification statement
60 tests, 12 mL
Product No. GA61961-2

RECOMMENDED COMPANION PRODUCTS

StepProductSize
Pre-treatmentEnVision™ FLEX Target Retrieval Solution, High pH (Code K8004)
3-in-1 procedure using PT Link
3 x 30 mL
Product No. K800421-2
Antibody Dilution
Ready-to-use / Prediluted
 
Negative ControlFLEX Negative Control, Mouse (Code IR750)
Positive tissue: Pancreas
120 tests, 24 mL
Product No. IR75066-2
Visualization SystemEnVision™ FLEX (Code K8000)
Use High pH Target Retrieval Solution
400-600 tests
Product No. K800021-2
CounterstainHematoxylin (Link) (Code K8008)
Non-aqueous, permanent mounting medium is required
3 x 45 mL, 400-600 tests
Product No. K800821-2
Glass SlidesFLEX IHC Microscope Slides (Code K8020)
Recommended for greater adherence
5 x 100 slides
Product No. K802021-2

  • Optimized staining performance of both high and low-expression structures
  • Crisp and clear staining with no background
  • Optimal laboratory efficiency with ready-to-use antibodies on Autostainer Link 48
The staining performance of all antibodies has been defined, tested and approved through collaboration with leading international pathologists. Check the Atlas of Stains - a guide to diagnostic accuracy.

ProductSize
For In Vitro Diagnostic UseIR619 RTU, FLEX
Safety Data Sheet:
Non-hazard classification statement
60 tests, 12 mL
Product No. IR61961-2

RECOMMENDED COMPANION PRODUCTS

StepProductSize
Pre-treatmentEnVision™ FLEX Target Retrieval Solution, High pH (Code K8004)
3-in-1 procedure using PT Link
3 x 30 mL
Product No. K800421-2
Antibody Dilution
Ready-to-use / Prediluted
 
Negative ControlFLEX Negative Control, Mouse (Code IS750)
Positive tissue: Pancreas
60 tests, 12 mL
Product No. IS75061-2
Visualization SystemEnVision™ FLEX (Code K8010)
Use High pH Target Retrieval Solution
400-600 tests
Product No. K801021
CounterstainHematoxylin (Dako Autostainer/Autostainer Plus) (Code K8018)
Non-aqueous, permanent mounting medium is required
10 x 13 mL, 400-600 tests
Product No. K801821-2
Glass SlidesFLEX IHC Microscope Slides (Code K8020)
Recommended for greater adherence
5 x 100 slides
Product No. K802021-2

  • Optimized staining performance of both high and low-expression structures
  • Crisp and clear staining with no background
  • Optimal laboratory efficiency with ready-to-use antibodies on Dako Autostainer Plus
The staining performance of all antibodies has been defined, tested and approved through collaboration with leading international pathologists. Check the Atlas of Stains - a guide to diagnostic accuracy.

ProductSize
For In Vitro Diagnostic UseIS619 RTU, FLEX
Safety Data Sheet:
Non-hazard classification statement
30 tests, 6 mL
Product No. IS61930-2

Synonym(s)

ck7, keratin

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