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Polyclonal Rabbit Anti-Human
Glucagon
The antibody strongly cross-reacts with glucagon in a large number of mammalian species.
- Frozen
- Formalin
- Excellent specificity
- High lot to lot consistency
- Optimized for immunohistochemistry (IHC) with validated protocols
- Certified manufacturing facilities guarantee full quality control
Intended Use
For in vitro diagnostic use.
Glucagon, a polypeptide of 29 amino acids, is one of seven known hormones produced in the pancreas. Glucagon, secreted by A-cells of the islets of Langerhans, elicits elevated blood glucose concentrations, stimulates intestinal fluid secretion and gastrin release and facilitates the inhibition of gastric and pancreatic secretions (1,2).The clinical interpretation of any positive staining or its absence should be complemented by morphological and histological studies with proper controls. Interpretation must be made within the context of the patient's clinical history and other diagnostic tests by a qualified pathologist.
Glucagon, a polypeptide of 29 amino acids, is one of seven known hormones produced in the pancreas. Glucagon, secreted by A-cells of the islets of Langerhans, elicits elevated blood glucose concentrations, stimulates intestinal fluid secretion and gastrin release and facilitates the inhibition of gastric and pancreatic secretions (1,2).The clinical interpretation of any positive staining or its absence should be complemented by morphological and histological studies with proper controls. Interpretation must be made within the context of the patient's clinical history and other diagnostic tests by a qualified pathologist.
Immunogen
Human glucagon
Specificity
The antibody has not been characterized by RIA techniques. Cross-reactivity with glucagon from other mammalian species was demonstrated by immunohistochemistry. This product has been optimized for use on human tissue.
Reagent Provided
Rabbit anti-glucagon is an unfractionated rabbit antiserum in 0.05 mol/L Tris-HCL, pH 7.6, and 0.015 mol/L sodium azide.
Protein concentration g/L: See label on vial.
Protein concentration g/L: See label on vial.
References
- Sternberger LA. In Immunocytochemistry, 2nd ed. New York: John Wiley and Sons 1979;8
- Unger RH and Orci L. Glucagon and the A cell. Physiology and patho physiology. N Eng J Med 1981; 304:1518
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| Product | Size |  | A0565 Whole serum
| 1 mL Product No. A056501-2 |
|---|