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Polyclonal Rabbit Anti-
Herpes Simplex Virus Type 1
The antigen used for immunization has been prepared by sonication and extraction of herpes simplex virus type 1-infected rabbit cornea cells. In the antigen all the virus proteins are present. The antibody reacts with type-specific, i.e. HSV-1, as well as with type-common, i.e. also with HSV-2, antigens.
- Frozen
- Formalin
- Excellent specificity
- High lot to lot consistency
- Optimized for immunohistochemistry (IHC) with validated protocols
- Certified manufacturing facilities guarantee full quality control
Intended Use
For in vitro diagnostic use.
Polyclonal Rabbit Anti-Herpes Simplex Virus Type 1 (MacIntyre) is well-suited for the detection of HSV in human cellular material obtained from superficial lesions or biopsies and for identification of HSV in infected tissue cultures. Interpretation of results must be made within the context of the patient's clinical history and other diagnostic tests by a certified professional.
Polyclonal Rabbit Anti-Herpes Simplex Virus Type 1 (MacIntyre) is well-suited for the detection of HSV in human cellular material obtained from superficial lesions or biopsies and for identification of HSV in infected tissue cultures. Interpretation of results must be made within the context of the patient's clinical history and other diagnostic tests by a certified professional.
Immunogen
Detergent-solubilized HSV type 1 (strain MacIntyre)-infected whole rabbit cornea cells (continuous cell line).
Specificity
The antibody reacts with HSV type 1 specific antigens and with antigens common for HSV types 1 and 2. The antibody reacts with all the majorglycoproteins present in the viral envelope and with at least one core protein as determined by crossed immunoelectrophoresis. Contaminating antibodies to human and bovine serum have been removed by solid-phase absorption.
In ELISA the antibody shows no reaction with human and bovine plasma. The antibody shows no cross-reactivity to cytomegalovirus andEpstein-Barr virus.
In indirect immunofluorescence a weak cross-reactivity to varicella zoster virus can be expected if the antibody is used in a relatively highconcentration. However, no cross-reactivity was found when the antibody was tested at a dilution of 1:100.
In ELISA the antibody shows no reaction with human and bovine plasma. The antibody shows no cross-reactivity to cytomegalovirus andEpstein-Barr virus.
In indirect immunofluorescence a weak cross-reactivity to varicella zoster virus can be expected if the antibody is used in a relatively highconcentration. However, no cross-reactivity was found when the antibody was tested at a dilution of 1:100.
Reagent Provided
Purified immunoglobulin fraction of rabbit antiserum provided in liquid form. In 0.1 mol/L NaCl, 15 mmol/L NaN3.
Protein concentration: See label on vial.
Protein concentration: See label on vial.
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| Product | Size |  | B0114 Ig fraction
| 2 mL Product No. B011402-2 |
|---|
For research use only. Not for use in diagnostic procedures.
FITC-Conjugated Polyclonal Rabbit Anti-Herpes Simplex Virus Type 1 (MacIntyre) is for detection of HSV in cellular material obtained from superficial lesions or biopsies and for identification of HSV in infected tissue cultures by direct immunofluorescence.
Immunogen
Detergent-solubilized HSV type 1 (strain MacIntyre)-infected whole rabbit cornea cells (continuous cell line).
Specificity
The antibody used reacts with HSV type 1 specific antigens and with antigens common to HSV types 1 and 2. The antibody reacts with all the major glycoproteins present in the viral envelope and at least one core protein as determined by crossed immunoelectrophoresis.
Contaminating antibodies to human and bovine serum have been removed by solid-phase absorption.
The antibody shows no reaction with human and bovine plasma when tested by ELISA. The antibody shows no cross-reactivity to cytomegalovirus and Epstein-Barr virus. A weak cross-reactivity to varicella zoster virus can be expected if the anti-body is used in a relatively high concentration. However, no cross-reactivity was found when the antibody used for conjugation was tested by the sensitive indirect immunofluorescence procedure at a dilution of 1:100.
Contaminating antibodies to human and bovine serum have been removed by solid-phase absorption.
The antibody shows no reaction with human and bovine plasma when tested by ELISA. The antibody shows no cross-reactivity to cytomegalovirus and Epstein-Barr virus. A weak cross-reactivity to varicella zoster virus can be expected if the anti-body is used in a relatively high concentration. However, no cross-reactivity was found when the antibody used for conjugation was tested by the sensitive indirect immunofluorescence procedure at a dilution of 1:100.
Reagent Provided
Purified immunoglobulin fraction of rabbit antiserum conjugated with fluorescein isothiocyanate isomer 1 provided is provided in liquid form in phosphate buffer containing 15 mmol/L NaN3, pH 7.2.
Protein concentration g/L: See label on vial.
F/P ratio: E495 nm/E278 nm = 0.65 ± 0.05 corresponding to a molar FITC/protein ratio of 2.3.
Protein concentration g/L: See label on vial.
F/P ratio: E495 nm/E278 nm = 0.65 ± 0.05 corresponding to a molar FITC/protein ratio of 2.3.
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| Product | Size |  | F0318 FITC. Ig fraction
| 2 mL Product No. F031802-8 |
|---|
Synonym(s) for Antigen
HSV, HSV-1, HSV1